Generation of a transgenic animal model of hyperthyroid Graves' disease
نویسندگان
چکیده
منابع مشابه
Motor neurone disease and hyperthyroid Graves' disease: a chance association?
The presentation of a 56-year-old woman with coexisting hyperthyroid Graves' disease and motor neurone disease is described. Circulating immune complexes were detected in the serum of seven patients with motor neurone disease (five cases) or primary lateral sclerosis (two cases), including a man with insulin-dependent diabetes mellitus.
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Dysprealbuminemic hyperthyroxinemia in a patient with hyperthyroid graves disease.
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متن کاملHyperthyroid graves disease--a 5 year retrospective study.
The clinical, biochemical and immunological features of 180 patients with hyperthyroid Graves' disease managed at the Universiti Kebangsaan Malaysia (UKM) Endocrine Clinic from 1983 to 1987 were examined. The prevalence of the disease is highest in Chinese and lowest in Indians. The female: male ratio is 2.8:1. Hypokalaemic periodic paralysis and hypercalcaemia were present in 5.0% and 1.7% of ...
متن کاملAnimal models of Graves' disease.
Graves' disease (GD) is an autoimmune condition in which goitre and hyperthyroidism are induced by thyroid stimulating antibodies (TSAB) which mimic the action of thyrotrophin (TSH). The target of the autoimmune response is the thyrotrophin receptor (TSHR) and, since its cloning, a number of differing approaches have been adopted in an attempt to develop an animal model of GD. Methods in which ...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2003
ISSN: 0014-2980,1521-4141
DOI: 10.1002/eji.200324255